It’s simple, neurotransmitters are the brain’s chemical messengers. They carry information across the tiny gaps (synapses) between nerve cells so your body can coordinate heartbeat and breathing, process memory, regulate mood, digest food, and react to the world in milliseconds. Without neurotransmitters, thoughts couldn’t form, muscles wouldn’t move, and organs couldn’t respond.

More importantly, by understanding these molecules we can begin understanding how electrical signals and chemistry work together to power a living mind.

How Neurotransmitters Work

Every message starts as an electrical impulse traveling down a neuron. When it reaches the synapse, the neuron releases neurotransmitter molecules packaged in vesicles. Those molecules cross the synaptic gap and bind to receptors on the next neuron, passing along the signal. Immediately after, enzymes break the transmitter down or the releasing neuron reabsorbs it—a rapid reset that prevents noisy, runaway signaling.

Interested in reading more? For a friendly overview, see the U.S. National Institute of Mental Health’s “Brain Basics.” (NIMH)

Major Neurotransmitters and What They Do

  • Dopamine — motivation, reward, movement initiation.
  • Serotonin — mood, appetite, sleep/wake balance.
  • Acetylcholine — muscle contraction, attention, memory formation.
  • GABA — the chief calming signal that reduces overactivity.
  • Glutamate — the chief excitatory signal for learning and memory.
  • Norepinephrine — alertness, focus, and the fight-or-flight response.

These molecules don’t work in isolation. They act like an orchestra: if one section is too loud or too quiet, the whole performance feels off. A detailed reference chapter on neurotransmitters and receptors is available through the U.S. National Library of Medicine’s NCBI Bookshelf. (NCBI Bookshelf)

You Can’t Make Signals Without Raw Materials

This is crazy but, your brain synthesizes neurotransmitters from everyday nutrients. Serotonin is made from the amino acid tryptophan; dopamine from tyrosine; acetylcholine from choline plus B-vitamins; GABA from glutamate. These conversions also require minerals (e.g., magnesium, iron, zinc, copper) as enzyme cofactors. When diets are low in quality protein, B-vitamins, or trace minerals, the brain may struggle to maintain optimal signaling.

The Fulvic Acid Connection: From Soil to Synapse

Neurotransmitter balance depends on having enough building blocks—and getting them into cells. That’s where fulvic acid comes in.

In living soils, fulvic acid helps shuttle minerals to plant roots. In people, it can help keep minerals and small organics mobile and available, supporting the “last mile” of nutrient delivery. We explored this soil-to-cell bridge in Nature’s Nutrient Key and the absorption story in The Missing Mineral.

Healthier soils → more mineral-dense foods → steadier neurotransmitter production.

Shared Chemistry in Plants, Microbes, and People

Plant and microbial worlds use similar chemical languages. Soil microbes can produce GABA- and serotonin-like molecules, and plants have glutamate signaling systems that help them respond to stress. Root exudates even “message” microbes to change behavior—an echo of how neurotransmitters coordinate networks in the human brain. The parallel is one reason we call the gut your “soil within,” a theme we expand on in Feeding the Soil Within.

When the Environment Interrupts the Conversation

Neurotransmission is sensitive to toxins and stressors. Heavy metals (e.g., lead, mercury), solvent exposures, and certain pesticides can disrupt synapses or damage neurons. The U.S. Environmental Protection Agency provides guidance on neurotoxicity and chemical risk evaluation. (EPA: Neurotoxicity) Chronic psychological stress, sleep loss, and ultra-processed diets can also alter signaling by depleting precursors and increasing inflammatory load.

Soil Health, Climate, and Brain Chemistry

Protecting soil biology doesn’t just help farms—it safeguards the nutrition that powers human brain chemistry. Practices that rebuild organic matter and fulvic/humic content improve mineral cycling and water retention. Those same practices help land store carbon, linking climate resilience to food quality and, indirectly, to neurotransmitter balance. For that bigger systems view, see The Carbon Key.

Practical Ways to Support Neurotransmitters

  • Eat for precursors: Include quality protein (amino acids), B-vitamins, and mineral-rich foods grown in living soil.
  • Support bioavailability: Consider clean, lab-tested fulvic acid to help deliver minerals and small organics to cells (consistent with the principles in The Missing Mineral).
  • Lower toxic load: Filter water where appropriate; reduce exposure to known neurotoxicants (see EPA resource above).
  • Protect the basics: Prioritize sleep, daylight exposure, movement, and stress regulation—habits that stabilize neurotransmission.

Healthy soil builds nutrient-dense food. Nutrient-dense food builds healthy neurotransmitters. Healthy neurotransmitters build a resilient mind.

Further Reading

Educational content only; not medical advice. If you have neurological symptoms or take medications affecting neurotransmitters, consult a qualified clinician. For agriculture or soil practices, consult local extension or conservation professionals.